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Article

Single-cell genomic analysis of cancer cells from one treatment-naïve patient with metastatic prostate cancer.

BMC genomic data - 8 May 2026

Jovel Juan, Polzer Bernhard, Patterson Jordan, Yong Hou, Vasquez Catalina, O'keefe Sandra, Pink Desmond, Li Guibo, Fairey Adrian, Adam Benjamin, Teitelbaum Jeremy, Salimi Amir, Kirsh Stefan, Alberter Barbara, Lowes Lori, Carpenter Eric, Kolinsky Michael, Zhu Zhongyi, Zhou Qing, Venner Peter, Venner Christopher, Williams David, Allan Alison, Boutros Paul C, Klein Christoph A, Wong Gane, Lewis John D

Abstract excerpt

BACKGROUND: Prostate cancer is among the most prevalent malignancies in men and a leading cause of cancer mortality worldwide. While localized prostate cancer is often curable, progression to metastatic and castration-resistant disease either in lymph nodes or bone/bone marrow remains the major cause of death. Understanding the genomic events that drive metastasis-particularly in treatment-naïve patients-is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42098607
DOI: 10.1186/s12863-026-01435-5
PMCID: PMC13326455

Genes

FOXO4
HRAS
MTOR
PTEN
RAF1
STAG2
TP53
VEGFB

Provenance

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