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Prospective clinical sequencing of 1016 Chinese prostate cancer patients: uncovering genomic characterization and race disparity.

Molecular oncology - 1 Oct 2023

Wei Yu, Zhang Tingwei, Wang Beihe, Pan Jian, Jin Shengming, Fang Bangwei, Gu Weijie, Qin Xiaojian, Dai Bo, Lin Guowen, Gan Hualei, Wu Junlong, Ye Dingwei, Zhu Yao

Abstract excerpt

Although there is a well-known disparity in prostate cancer (PC) incidence and mortality between Chinese and Western patients, the underlying genomic differences have been investigated only sparsely. This clinicogenomic study was conducted to reveal the genomic mutations contributing to the PC disparity across ethnicities and investigate the mutational profile of Chinese PC patients. A total of 1016 Chinese PC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37584393
DOI: 10.1002/1878-0261.13511
PMCID: PMC10552897

Genes

PC
FOXA1
TP53
APC
AR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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