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Article

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.

Cell death & disease - 7 Jun 2018

Zhou Qiang-Hua, Deng Chuang-Zhong, Li Zai-Shang, Chen Jie-Ping, Yao Kai, Huang Kang-Bo, Liu Ting-Yu, Liu Zhuo-Wei, Qin Zi-Ke, Zhou Fang-Jian, Huang Wenlin, Han Hui, Liu Ran-Yi

Abstract excerpt

Cell line models are essential tools to study the molecular mechanisms underlying tumor initiation and progression. There are limited treatment options for penile squamous cell carcinoma (PSCC), accounting for 1-2% of male tumors in developing countries, and limited progress in preclinical research in PSCC due to lacking available models with identified genomic characteristics. Here, biological and molecular...

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Identifiers

PMID: 29880898
DOI: 10.1038/s41419-018-0736-1
PMCID: PMC5992159

Genes

EGFR
BCLAF1
CLTCL1
ERCC5
FANCD2
FANCE
HRAS
MYC
NCOA2
NOTCH1
NOTCH2
PLAG1
TET2
USP6
XPC

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