Article

Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress

2023-09-01

Abstract excerpt

Cells react to stress by triggering response pathways, leading to extensive alterations in the transcriptome to restore cellular homeostasis. The role of RNA metabolism in shaping the cellular response to stress is vital, yet the global changes in RNA stability under these conditions remain unclear. In this work, we employ direct RNA sequencing with nanopores, enhanced by 5’ end adaptor ligation, to comprehensivel...

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Literature Corpus work: 99f4489a-a7e0-5016-8c8c-955bcfd04eee
DOI: 10.1101/2023.08.31.555629

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