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Article

Stress-specific differences in assembly and composition of stress granules and related foci.

Journal of cell science - 1 Mar 2017

Aulas Anaïs, Fay Marta M, Lyons Shawn M, Achorn Christopher A, Kedersha Nancy, Anderson Paul, Ivanov Pavel

Abstract excerpt

Cells have developed different mechanisms to respond to stress, including the formation of cytoplasmic foci known as stress granules (SGs). SGs are dynamic and formed as a result of stress-induced inhibition of translation. Despite enormous interest in SGs due to their contribution to the pathogenesis of several human diseases, many aspects of SG formation are poorly understood. SGs induced by different stresses...

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Identifiers

PMID: 28096475
DOI: 10.1242/jcs.199240
PMCID: PMC5358336

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