Article

Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

2024-07-26

Abstract excerpt

RNAs undergo a complex choreography of metabolic processes in human cells that are regulated by thousands of RNA-associated proteins. While the effects of individual RNA-associated proteins on RNA metabolism have been extensively characterized, the full complement of regulators for most RNA metabolic events remain unknown. Here we present a massively parallel RNA-linked CRISPR (ReLiC) screening approach to measure...

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Literature Corpus work: 5e99f208-991f-5f7c-82e5-1bc90a35f777
DOI: 10.1101/2024.07.25.605204

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