Article
Metabolic T-cell phenotypes: from bioenergetics to function.
American journal of physiology. Cell physiology - 1 Mar 2025
Jantz-Naeem Nouria, Guvencli Nese, Böttcher-Loschinski Romy, Böttcher Martin, Mougiakakos Dimitrios, Kahlfuss Sascha
Abstract excerpt
It is well known that T-cell metabolism and function are intimately linked. Metabolic reprogramming is a dynamic process that provides the necessary energy and biosynthetic precursors while actively regulating the immune response of T cells. As such, aberrations and dysfunctions in metabolic (re)programming, resulting in altered metabolic endotypes, may have an impact on disease pathology in various contexts....
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