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Differential cellular immune responses against <i>Orientia tsutsugamushi</i> Karp and Gilliam strains following acute infection in mice

2023-06-08

Abstract excerpt

Scrub typhus is the leading source of febrile illness in endemic countries due to infection with Orientia tsutsugamushi ( Ot ), a seriously understudied intracellular bacterium. Pulmonary complications in patients are common and can develop into life threatening conditions. The diverse antigenicity of Ot genotypes and inter-strain differences seem to be connected to varied virulence and clinical outcomes; howev...

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Literature Corpus work
99697a87-9d2c-5cd0-b329-181f5cdffc33
DOI
10.1101/2023.06.07.543994
Open publication

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