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Comparative Dual RNA-Seq Analysis of Eight <i>Orientia tsutsugamushi</i> Strains in Endothelial Cells Reveals Regulatory Patterns in Bacterial and Host Pathways During Infection

2025-12-01

Abstract excerpt

Orientia tsutsugamushi is an obligate intracellular bacterium that causes the mite-borne human disease scrub typhus. The species is characterised by having many strains that differ in their ability to cause disease in murine infection models and in human patients. The genomes of a diverse set of Orientia tsutsugamushi strains have recently been analysed in detail, revealing broadly similar gene content with genom...

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Literature Corpus work
bfde8d22-277b-59c1-aa28-d6abf004889a
DOI
10.1101/2025.12.01.691569
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Comparative Dual RNA-Seq Analysis of Eight <i>Orientia tsutsugamushi</i> Strains in Endothelial Cells Reveals Regulatory Patterns in Bacterial and Host Pathways During InfectionDOI 10.1101/2025.12.01.691569
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