Article

Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling

2021-05-23

Abstract excerpt

<h4>SUMMARY</h4> Wnt signaling is essential for many aspects of embryonic development including the formation of the primary embryonic axis. In addition, excessive Wnt signaling drives multiple diseases including cancer highlighting its importance for disease pathogenesis. β-catenin is a key effector in this pathway that translocates into the nucleus and activates Wnt responsive genes. However, due to our lack of...

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Literature Corpus work: 2d29a770-e448-5027-93ce-86d7757622de
DOI: 10.1101/2021.05.22.445277

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