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Article

Wnt/beta-catenin signaling.

Cytokine & growth factor reviews - 1 Dec 2000

Akiyama T

Abstract excerpt

The Wnt/Wingless signaling transduction pathway plays an important role in both embryonic development and tumorigenesis. beta-Catenin, a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of transcription factors and activates transcription of Wnt target genes. Recent studies have revealed that a number of proteins such as, the tumor suppressor APC and Axin are involved in the...

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Identifiers

PMID: 10959075
DOI: 10.1016/s1359-6101(00)00011-3

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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