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Article

Mendelian Randomization with Instrumental Variable Synthesis (IVY)

2019-09-09

Abstract excerpt

<h4>SUMMARY</h4> Mendelian Randomization (MR) is an important causal inference method primarily used in biomedical research. This work applies contemporary techniques in machine learning to improve the robustness and power of traditional MR tools. By denoising and combining candidate genetic variants through techniques from unsupervised probabilistic graphical models, an influential latent instrumental variable i...

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Literature Corpus work
97bc42d1-bce6-593b-9378-2b08b5a7dc36
DOI
10.1101/657775
Open publication

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Mendelian Randomization with Instrumental Variable Synthesis (IVY)DOI 10.1101/657775
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