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Article

Mendelian Randomization: New Applications in the Coming Age of Hypothesis-Free Causality.

Annual review of genomics and human genetics - 1 Jan 2015

Evans David M, Davey Smith George

Abstract excerpt

Mendelian randomization (MR) is an approach that uses genetic variants associated with a modifiable exposure or biological intermediate to estimate the causal relationship between these variables and a medically relevant outcome. Although it was initially developed to examine the relationship between modifiable exposures/biomarkers and disease, its use has expanded to encompass applications in molecular...

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Identifiers

PMID: 25939054
DOI: 10.1146/annurev-genom-090314-050016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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