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Article

A review of instrumental variable estimators for Mendelian randomization.

Statistical methods in medical research - 1 Oct 2017

Burgess Stephen, Small Dylan S, Thompson Simon G

Abstract excerpt

Instrumental variable analysis is an approach for obtaining causal inferences on the effect of an exposure (risk factor) on an outcome from observational data. It has gained in popularity over the past decade with the use of genetic variants as instrumental variables, known as Mendelian randomization. An instrumental variable is associated with the exposure, but not associated with any confounder of the...

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Identifiers

PMID: 26282889
DOI: 10.1177/0962280215597579
PMCID: PMC5642006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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