Article
[Mendelian randomization approach, used for causal inferences].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Apr 2017
Wang L N, Zhang Zuofeng
Abstract excerpt
Mendelian randomization (MR) approach is based on the Mendelian genetic law, which is called "Parental alleles that randomly assigned to the offspring" . MR refers to the use of genetic variants to develop causal inferences from observational data, if the variant genotype is associated with the phenotype and the variant genotype associated with the risk of disease of interest through the phenotype. Hence, the...
Topics
- Alleles
- Causality
- Epidemiologic Methods
- Genetic Variation
- Genotype
- Humans
- Mendelian Randomization Analysis
- Observational Studies as Topic
- Random Allocation
- Reproducibility of Results