Article

Dual Lineage Tracing Identifies Cellular Mechanisms Underlying Radiation-Associated Changes in Atherosclerotic Lesion Composition

2026-01-15

Abstract excerpt

<h4>Background</h4> Phenotypic plasticity of smooth muscle cells (SMCs) and endothelial cells (ECs) contributes to atherosclerotic plaque composition and stability, yet how shifts in one population influence the contribution and function of the other under conditions of vascular stress, such as irradiation, is poorly understood. A major limitation has been the inability to simultaneously fate-map both cell types...

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Literature Corpus work: 9702ed3f-d4bd-5777-929c-c25b7629cb1c
DOI: 10.64898/2026.01.14.699566

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