Article
Atherosclerosis is a smooth muscle cell-driven tumor-like disease
2023-03-07
Abstract excerpt
Atherosclerosis, the leading cause of cardiovascular disease, is a chronic inflammatory disease involving pathological activation of multiple cell types, such as immunocytes (e.g., macrophage, T cells), smooth muscle cells (SMCs), and endothelial cells. Multiple lines of evidence have suggested that SMC “phenotypic switching” plays a central role in atherosclerosis development and complications. Yet, SMC roles and...
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Identifiers and source
- Literature Corpus work
- d6495da6-c965-5684-a4fd-d99ec93b9e09
- DOI
- 10.1101/2023.03.06.531330
