Article

Role of AMPK in Atrial Metabolic Homeostasis and Substrate Preference

2024-08-30

Abstract excerpt

<h4>Summary</h4> Atrial fibrillation is the most common clinical arrhythmia and may be due in part to metabolic stress. Atrial specific deletion of the master metabolic sensor, AMP-activated protein kinase (AMPK), induces atrial remodeling culminating in atrial fibrillation in mice, implicating AMPK signaling in the maintenance of atrial electrical and structural homeostasis. However, atrial substrate preference...

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Literature Corpus work: 968d3fc5-4cd9-5b24-9c08-92df512c5f3a
DOI: 10.1101/2024.08.29.608789

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