Article
AMP-activated protein kinase: a core signalling pathway in the heart.
Acta physiologica (Oxford, England) - 1 May 2009
Kim A S, Miller E J, Young L H
Abstract excerpt
Over the past decade, AMP-activated protein kinase (AMPK) has emerged as an important intracellular signalling pathway in the heart. Activated AMPK stimulates the production of ATP by regulating key steps in both glucose and fatty acid metabolism. It has an inhibitory effect on cardiac protein synthesis. AMPK also interacts with additional intracellular signalling pathways in a coordinated network that modulates...
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