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Article

AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart.

Progress in lipid research - 1 May 2003

Sambandam Nandakumar, Lopaschuk Gary D

Abstract excerpt

Myocardial ischemia is the leading cause of all cardiovascular deaths in North America. Myocardial ischemia is accompanied by profound changes in metabolism including alterations in glucose and fatty acid metabolism, increased uncoupling of glucose oxidation from glycolysis and accumulation of protons within the myocardium. These changes can contribute to a poor functional recovery of the heart. One key player in...

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PMID: 12689619
DOI: 10.1016/s0163-7827(02)00065-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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