Article
The molecular and functional identities of atrial cardiomyocytes in health and disease.
Biochimica et biophysica acta - 1 Jul 2016
Brandenburg Sören, Arakel Eric C, Schwappach Blanche, Lehnart Stephan E
Abstract excerpt
Atrial cardiomyocytes are essential for fluid homeostasis, ventricular filling, and survival, yet their cell biology and physiology are incompletely understood. It has become clear that the cell fate of atrial cardiomyocytes depends significantly on transcription programs that might control thousands of differentially expressed genes. Atrial muscle membranes propagate action potentials and activate myofilament...
Topics
- Action Potentials
- Animals
- Atrial Fibrillation
- Atrial Function
- Atrial Remodeling
- Calcium Signaling
- Cell Differentiation
- Cell Lineage
- Heart Atria
- Humans
- Myocardial Contraction
