Article

Metabolic Profiling of Aortic Stenosis and Hypertrophic Cardiomyopathy Identifies Mechanistic Contrasts in Substrate Utilisation

2019-08-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Aortic stenosis (AS) and hypertrophic cardiomyopathy (HCM) are highly distinct disorders leading to left ventricular hypertrophy (LVH), but whether cardiac metabolism substantially differs between these in humans remains to be elucidated. <h4>Method</h4> We undertook a detailed invasive (aortic root and coronary sinus) metabolic profiling in patients with severe AS and HCM...

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Literature Corpus work: ac1e574f-bc18-53ee-a90e-976047e19330
DOI: 10.1101/715680

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