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Characterisation of the <i>in-vivo</i> miRNA landscape in <i>Drosophila</i> ribonuclease mutants reveals Pacman mediated regulation of the highly conserved <i>let-7</i> cluster during apoptotic processes

2023-05-30

Abstract excerpt

<h4>ABSTRACT</h4> The control of gene expression is a fundamental process essential for correct development and to maintain homeostasis. Many post-transcriptional mechanisms exist to maintain the correct levels of each RNA transcript within the cell. Controlled and targeted cytoplasmic RNA degradation is one such mechanism with the 5’-3’ exoribonuclease Pacman (XRN1) and the 3’-5’ exoribonuclease Dis3L2 playing c...

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Literature Corpus work
963e3797-a793-5ced-91a6-9ffaf1d8535e
DOI
10.1101/2023.05.30.542828
Open publication

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Characterisation of the <i>in-vivo</i> miRNA landscape in <i>Drosophila</i> ribonuclease mutants reveals Pacman mediated regulation of the highly conserved <i>let-7</i> cluster during apoptotic processesDOI 10.1101/2023.05.30.542828
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