Article
Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals
2023-06-26
Abstract excerpt
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression that play critical roles in development and disease. Target-directed miRNA degradation (TDMD), a pathway in which miRNAs that bind to specialized targets with extensive complementarity are rapidly decayed, has emerged as a potent mechanism of controlling miRNA levels. Nevertheless, the biological role and scope of miRNA regulation by TDMD in...
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Identifiers and source
- Literature Corpus work
- 04f7d750-7b00-5550-adaf-5f21f21032ad
- DOI
- 10.1101/2023.06.26.546601