Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 5'-3' exoribonuclease pacman is required for epithelial sheet sealing in Drosophila and genetically interacts with the phosphatase puckered.

Biology of the cell - 1 Dec 2008

Grima Dominic P, Sullivan Melanie, Zabolotskaya Maria V, Browne Cathy, Seago Julian, Wan Kay Chong, Okada Yoshio, Newbury Sarah F

Abstract excerpt

BACKGROUND INFORMATION: Ribonucleases have been well studied in yeast and bacteria, but their biological significance to developmental processes in multicellular organisms is not well understood. However, there is increasing evidence that specific timed transcript degradation is critical for regulation of many cellular processes, including translational repression, nonsense-mediated decay and RNA interference....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Epithelium

Share to Exoribonucleases

Share to JNK Mitogen-Activated Protein Kinases

Share to Phosphoprotein Phosphatases

Source

Identifiers

PMID: 18547166
DOI: 10.1042/BC20080049

Genes

XRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 5'-3' exoribonuclease pacman is required for epithelial sheet sealing in Drosophila and genetically interacts with the phosphatase puckered.PMID 18547166Read ↗

The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs.Semantic proximity Read ↗

Characterisation of the <i>in-vivo</i> miRNA landscape in <i>Drosophila</i> ribonuclease mutants reveals Pacman mediated regulation of the highly conserved <i>let-7</i> cluster during apoptotic processesSemantic proximity Read ↗

Identification and developmental expression of a 5'-3' exoribonuclease from Drosophila melanogaster.Semantic proximity Read ↗

RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1.Semantic proximity Read ↗

The roles of the exoribonucleases DIS3L2 and XRN1 in human diseaseSemantic proximity Read ↗

XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Semantic proximity Read ↗

Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases.Semantic proximity Read ↗

piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline.Semantic proximity Read ↗

Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae.Semantic proximity Read ↗

Disruption of the protein kinase N gene of drosophila melanogaster results in the recessive delorean allele (pkndln) with a negative impact on wing morphogenesis.Semantic proximity Read ↗

High-throughput siRNA screening reveals functional interactions and redundancies of human processive exoribonucleasesSemantic proximity Read ↗

Likely foregut endoderm origin for a postzygotic mutation affecting the RNase IIIb domain of DICER1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.