microRNAs in Drosophila regulate cell fate by repressing single mRNA targets.

doi:10.1387/ijdb.160271ht

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Article

microRNAs in Drosophila regulate cell fate by repressing single mRNA targets.

The International journal of developmental biology - 1 Jan 2017

Perry Noam, Volin Marina, Toledano Hila

Abstract excerpt

Regulation of gene expression governs all aspects of the lifespan of the organism, such as embryonic development, stem cell differentiation, reproduction and aging. Among the most important regulators of these extremely complex processes are microRNAs (miRNAs), small non-coding RNAs that repress gene expression by binding to primary sequences on the mRNA of their target. Theoretically, the mere existence of a...

Topics

Animals
Cell Differentiation
Cell Lineage
Computational Biology
Disease Models, Animal
Down-Regulation
Drosophila melanogaster
Gene Expression Regulation, Developmental
Genome
Humans
MicroRNAs
Molecular Biology
Phenotype
Protein Interaction Mapping
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 28621414
DOI: 10.1387/ijdb.160271ht

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