Article

An atlas of genetic effects on the monocyte methylome across European and African populations

2024-08-13

Abstract excerpt

Elucidating the genetic architecture of DNA methylation (DNAm) is crucial for decoding complex disease etiology. However, current epigenomic studies are often constrained by limited methylation coverage and tissue heterogeneity. Here, we present the first comprehensive, multi-ancestry methylome atlas of purified human monocytes, which play a central role in immune response and inflammation, generated through integ...

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Literature Corpus work: 953ceb47-b219-5855-af24-22b25e883b48
DOI: 10.1101/2024.08.12.24311885

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