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Article

Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.

Epigenetics - 1 Sept 2014

Gunawardhana Lakshitha P, Gibson Peter G, Simpson Jodie L, Benton Miles C, Lea Rodney A, Baines Katherine J

Abstract excerpt

Epigenetic changes including DNA methylation caused by environmental exposures may contribute to the heterogeneous inflammatory response in asthma. Here we investigate alterations in DNA methylation of purified blood monocytes that are associated with inflammatory phenotypes of asthma. Peripheral blood was collected from adults with eosinophilic asthma (EA; n = 21), paucigranulocytic asthma (PGA; n = 22),...

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Identifiers

PMID: 25147914
DOI: 10.4161/epi.33066
PMCID: PMC4169022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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