Article

Three Distinct Transcriptional Profiles of Monocytes Associate with Disease Activity in SSc Patients

2022-02-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background/Purpose</h4> Patients with systemic sclerosis (SSc) display a complex clinical phenotype. There are numerous studies that relate transcriptional signatures from PBMC or whole skin of SSc patients to disease activity. However, analyses of whole tissue RNA-sequencing studies are subjected to changes in cellular composition that can drive gene expression signatures and a loss of the...

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Literature Corpus work: 2b61e2d3-61f2-5242-b9ba-7bff18f88869
DOI: 10.1101/2022.01.29.477568

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