Article

Neural CXCR4 contributes to neuroimmune modulation of atherosclerosis in a cardio-metabolic Ldlr⁻/⁻ mouse model

2025-12-18

Abstract excerpt

<h4>Background</h4> Atherosclerosis is a chronic inflammatory disease characterized by metabolic and immune dysregulation. Emerging evidence suggests that specific central nervous system (CNS) regions modulate its progression via neuroimmune cardiovascular interfaces (NICIs). While the C-X-C motif chemokine receptor 4 (CXCR4) is known to participate in atherogenesis by regulating immune cell dynamics and vascular...

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Literature Corpus work: 94f2d72d-b707-5286-bffa-cdfc838ff6aa
DOI: 10.64898/2025.12.16.694604

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