Article

HiCInterpolate: 4D Spatiotemporal Interpolation of Hi-C Data for Genome Architecture Analysis

2026-02-09

Abstract excerpt

<h4>Motivation</h4> Studying the three-dimensional (3D) structure of a genome, including chromatin loops and Topologically Associating Domains (TADs), is essential for understanding how the genome is organized, such as gene activation, cell development, protein-protein interaction, etc. Hi-C protocol enables us to study 3D genome structure and organization. Chromatin 3D structure changes dynamically over time, an...

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Literature Corpus work: 94ab7056-0006-5f9d-8964-ada159bea384
DOI: 10.64898/2026.02.06.704438

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