Article

SARS-CoV-2 Spike receptor-binding domain with a G485R mutation in complex with human ACE2

2021-03-17

Abstract excerpt

Since SARS-CoV-2 emerged in 2019, genomic sequencing has identified mutations in the viral RNA including in the receptor-binding domain of the Spike protein. Structural characterisation of the Spike carrying point mutations aids in our understanding of how these mutations impact binding of the protein to its human receptor, ACE2, and to therapeutic antibodies. The Spike G485R mutation has been observed in multiple...

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Literature Corpus work: 949bda7d-60bc-5f30-a67b-c71d58d1a5e2
DOI: 10.1101/2021.03.16.434488

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