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Article

Mutations in the receptor-binding domain of human SARS CoV-2 spike protein increases its affinity to bind human ACE-2 receptor.

Journal of biomolecular structure & dynamics - 1 Apr 2023

Naresh Gatta K R S, Guruprasad Lalitha

Abstract excerpt

The severe acute respiratory syndrome virus-2 (SARS CoV-2) infection has resulted in the current global pandemic. The binding of SARS CoV-2 spike protein receptor-binding domain (RBD) to the human angiotensin converting enzyme-2 (ACE-2) receptor causes the host infection. The spike protein has undergone several mutations with reference to the initial strain isolated during December 2019 from Wuhan, China. A...

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PMID: 35109768
DOI: 10.1080/07391102.2022.2032354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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