Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Spike of Concern-The Novel Variants of SARS-CoV-2.

Viruses - 27 May 2021

Winger Anna, Caspari Thomas

Abstract excerpt

The high sequence identity of the first SARS-CoV-2 samples collected in December 2019 at Wuhan did not foretell the emergence of novel variants in the United Kingdom, North and South America, India, or South Africa that drive the current waves of the pandemic. The viral spike receptor possesses two surface areas of high mutagenic plasticity: the supersite in its N-terminal domain (NTD) that is recognised by all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to COVID-19
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Models, Molecular

Share to Protein Conformation

Share to SARS-CoV-2

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 34071984
DOI: 10.3390/v13061002
PMCID: PMC8229995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Spike of Concern-The Novel Variants of SARS-CoV-2.PMID 34071984Read ↗

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein.Semantic proximity Read ↗

Epidemiology and Characteristics of SARS-CoV-2 Variants of Concern: The Impacts of the Spike MutationsSemantic proximity Read ↗

SARS-CoV-2 Spike receptor-binding domain with a G485R mutation in complex with human ACE2Semantic proximity Read ↗

Understanding Mutations in Human SARS-CoV-2 Spike Glycoprotein: A Systematic Review & Meta-Analysis.Semantic proximity Read ↗

Mutation informatics: SARS-CoV-2 receptor-binding domain of the spike protein.Semantic proximity Read ↗

Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasionSemantic proximity Read ↗

Mutation-Induced Long-Range Allosteric Interactions in the Spike Protein Determine the Infectivity of SARS-CoV-2 Emerging VariantsSemantic proximity Read ↗

The lethal triad: SARS-CoV-2 Spike, ACE2 and TMPRSS2. Mutations in host and pathogen may affect the course of pandemicSemantic proximity Read ↗

Structure-function relations of the SARS-CoV-2 spike protein and impact of mutations in the variants of concern.Semantic proximity Read ↗

Preliminary report on SARS-CoV-2 Spike mutation T478KSemantic proximity Read ↗

Unraveling the stability landscape of mutations in the SARS-CoV-2 receptor-binding domain.Semantic proximity Read ↗

Emerging mutation in SARS-CoV-2 spike: Widening distribution over time in different geographic areas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.