Article

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development

2023-10-02

Abstract excerpt

<title>Abstract</title> <p>Non-coding variants increase risk of neuropsychiatric disease. However, our understanding of the cell-type specific role of the non-coding genome in disease is incomplete. We performed population scale (N=1,393) chromatin accessibility profiling of neurons and non-neurons from two neocortical brain regions: the anterior cingulate cortex and dorsolateral prefrontal cortex. Across both re...

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Literature Corpus work: 94818d75-fc82-589c-b1bf-ee42778fd431
DOI: 10.21203/rs.3.rs-3393581/v1

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