Article

Sex differences in brain cell-type specific chromatin accessibility in schizophrenia

2024-04-04

Abstract excerpt

<title>Abstract</title> <p> Our understanding of the sex-specific role of the non-coding genome in serious mental illness remains largely incomplete. To address this gap, we explored sex differences in 1,393 chromatin accessibility profiles, derived from neuronal and non-neuronal nuclei of two distinct cortical regions from 234 cases with serious mental illness and 235 controls. We identified sex-specific enhanc...

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Literature Corpus work: 989bba62-63a7-5f86-a149-58ee231d4ffe
DOI: 10.21203/rs.3.rs-4158509/v1

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