Article

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development

2023-10-03

Abstract excerpt

Non-coding variants increase risk of neuropsychiatric disease. However, our understanding of the cell-type specific role of the non-coding genome in disease is incomplete. We performed population scale (N=1,393) chromatin accessibility profiling of neurons and non-neurons from two neocortical brain regions: the anterior cingulate cortex and dorsolateral prefrontal cortex. Across both regions, we observed notable d...

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Literature Corpus work: 08ae708d-ddb8-5055-8309-a797b56785a8
DOI: 10.1101/2023.10.02.23296067

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