Article
Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2021
Kouakou Manuela R, Cameron Darren, Hannon Eilis, Dempster Emma L, Mill Jonathan, Hill Matthew J, Bray Nicholas J
Abstract excerpt
Common genetic variation appears to largely influence risk for neuropsychiatric disorders through effects on gene regulation. It is therefore possible to shed light on the biology of these conditions by testing for enrichment of associated genetic variation within regulatory genomic regions operating in specific tissues or cell types. Here, we have used the assay for transposase-accessible chromatin with...
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