Article
Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders
2021-09-01
Abstract excerpt
Common genetic variation appears to largely influence risk for neuropsychiatric disorders through effects on gene regulation. It is therefore possible to shed light on the biology of these conditions by testing for enrichment of associated genetic variation within regulatory genomic regions operating in specific tissues or cell types. Here, we have used ATAC-Seq to map open chromatin (an index of active regulatory...
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Identifiers and source
- Literature Corpus work
- 33356164-00bf-5099-b23e-0b2a56cd142c
- DOI
- 10.1101/2021.09.01.458548