Article

Candidate targets of copy number deletion events across 17 cancer types

2022-06-30

Abstract excerpt

Genome variation is the direct cause of cancer and driver of its clonal evolution. While the impact of many point mutations can be evaluated through their modification of individual genomic elements, even a single copy number aberration (CNA) may encompass hundreds of genes and therefore pose challenges to untangle potentially complex functional effects. However, consistent, recurring and disease-specific patterns...

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Literature Corpus work: fbd1c6f8-9816-5282-b193-8164ca0f1d4f
DOI: 10.1101/2022.06.29.498080

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