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Article

A broad-host-range CRISPRi toolkit for silencing gene expression in <i>Burkholderia</i>

2019-04-26

Abstract excerpt

Genetic tools are critical to dissecting the mechanisms governing cellular processes, from fundamental physiology to pathogenesis. Members of the genus Burkholderia have potential for biotechnological applications but can also cause disease in humans with a debilitated immune system. The lack of suitable genetic tools to edit Burkholderia GC-rich genomes has hampered the exploration of useful capacities and the...

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Literature Corpus work
945f4606-8a96-5e37-8a28-ad7a054e7c29
DOI
10.1101/618413
Open publication

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A broad-host-range CRISPRi toolkit for silencing gene expression in <i>Burkholderia</i>DOI 10.1101/618413
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