Article

<i>Plcg2</i> <sup> <i>M28L</i> </sup> interacts with high fat-high sugar diet to accelerate Alzheimer’s disease-relevant phenotypes in mice

2022-02-12

Abstract excerpt

Obesity is recognized as a significant risk factor for Alzheimer’s disease (AD). Studies have supported the notion that obesity accelerates AD-related pathophysiology in mouse models of AD. The majority of studies to date have focused on the use of early-onset AD models. Here we evaluate the impact of genetic risk factors on late-onset AD (LOAD) in mice fed a high fat/high sugar diet. We focused on three mouse mod...

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Literature Corpus work: 945b773c-81bb-5094-8849-4656a5896bb0
DOI: 10.1101/2022.02.11.480032

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<i>Plcg2</i> <sup> <i>M28L</i> </sup> interacts with high fat-high sugar diet to accelerate Alzheimer’s disease-relevant phenotypes in miceDOI 10.1101/2022.02.11.480032Read

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