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Young APPKI <sup>NL-G-F/NL-G-F</sup> mice display high-fat diet-induced metabolic disturbances and specific disorders associated with brain energy homeostasis

2021-12-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aim</h4> Type 2 diabetes mellitus (T2DM) is an increased risk factor for Alzheimer’s disease (AD); however, the relationship between the two conditions is controversial. High-fat diet (HFD) causes cognitive impairment with/without Aβ accumulation in middle-aged or aged transgenic (Tg) and knock-in (KI) AD mouse models, except for metabolic disorders, which commonly occur in all mice types....

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Literature Corpus work
69dc1b08-0c83-5d45-a8d1-3966f4fd06b9
DOI
10.1101/2021.12.21.473697
Open publication

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Young APPKI <sup>NL-G-F/NL-G-F</sup> mice display high-fat diet-induced metabolic disturbances and specific disorders associated with brain energy homeostasisDOI 10.1101/2021.12.21.473697
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