Article

Discovery of GluA3 preferring AMPA receptor positive allosteric modulator BRD3290

2026-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia is a debilitating neuropsychiatric disease that lacks effective treatments for many symptom domains including negative, cognitive and sleep disturbances. Lack of clear disease etiology has hampered the development of new, effective treatments for the unmet needs of people with schizophrenia. Large scale human genetics have identified rare loss of function mutations that substantial...

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Literature Corpus work: 9459fe46-b1c9-5c4f-8074-2ab60e0fd80a
DOI: 10.64898/2026.07.26.740780

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