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Article

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes.

Nature reviews. Drug discovery - 29 Jul 2011

Rudolph Uwe, Knoflach Frédéric

Abstract excerpt

GABA(A) (γ-aminobutyric acid, type A) receptors are a family of ligand-gated ion channels that are essential for the regulation of central nervous system function. Benzodiazepines - which non-selectively target GABA(A) receptors containing the α1, α2, α3 or α5 subunits - have been in clinical use for decades and are still among the most widely prescribed drugs for the treatment of insomnia and anxiety disorders....

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Identifiers

PMID: 21799515
DOI: 10.1038/nrd3502
PMCID: PMC3375401

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Source receipt: pubmed, retrieved 7 Sept 2026.

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