Article

Tau-mediated axonal degeneration is prevented by activation of the Wld <sup>S</sup> pathway

2020-12-07

Abstract excerpt

Tauopathy is characterised by neuronal dysfunction and degeneration occurring as a result of changes to the microtubule associated protein tau. The neuronal changes evident in Tauopathy bear striking morphological resemblance to those reported in models of Wallerian degeneration. The mechanisms underpinning Wallerian degeneration are not fully understood although it can be delayed by the expression of the slow Wal...

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Literature Corpus work: 9453dd9c-b85d-5f43-aa08-27716bbdfbc7
DOI: 10.1101/2020.12.06.408583

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