Article

Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane

2022-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed treatment for individuals experiencing major depressive disorder (MDD). The therapeutic mechanisms that take place before, during, or after SSRIs bind the serotonin transporter (SERT) are poorly understood, partially because no studies exist of the cellular and subcellular pharmacokinetic properties of SSRIs in living cells....

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Literature Corpus work: 93ba46a6-78b3-565c-a0a2-37fcb0c88d2e
DOI: 10.1101/2022.08.09.502705

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