Article

Fluorescent non-canonical amino acid provides mechanistic insight into the human serotonin transporter

2024-01-25

Abstract excerpt

<title>Abstract</title> <p>The serotonin transporter (SERT), responsible for the reuptake of released serotonin, serves as a major target for antidepressants and psychostimulants. Nevertheless, refining the mechanistic models for SERT remains challenging. Here, we bridge the structural and functional understanding of SERT by incorporating the fluorescent non-canonical amino acid Anap through genetic code expansio...

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Literature Corpus work: bc7c14cc-c39f-5894-b281-b30e7033bd27
DOI: 10.21203/rs.3.rs-3792735/v1

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