Article

Subtyping Schizophrenia Using Psychiatric Polygenic Scores

2023-10-13

Abstract excerpt

<h4>Background</h4> Subtyping schizophrenia can disentangle heterogeneity and help with treatment decision- making. However, current schizophrenia subtypes have not demonstrated adequate clinical utility, limited by sample size, suboptimal clustering methods, and choice of clustering input. Polygenic scores (PGS) reflect the genetic risk of phenotypes including comorbidities and are available before treatment, mak...

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Literature Corpus work: 93624251-1af6-57ec-a7ee-62a1d4cb68a9
DOI: 10.1101/2023.10.12.23296915

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