Article

Early astrocytic dysfunction is associated to mistuned synapses as well as anxiety and depressive-like behavior in the AppNL-F mouse model of Alzheimers disease

2023-05-12

Abstract excerpt

Alzheimers disease is the most common neurodegenerative disease and constitute 75% of dementia cases worldwide. Unfortunately, efficient and affordable treatments are still lacking for this mental illness, it is therefore urgent to identify new pharmacological targets. Whereas the late phases of the disease are well described, recent evidence suggest synaptic impairments at a pre-amyloid β; (Aβ) plaque stage. Astr...

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Literature Corpus work: 933315a6-77de-5dae-906d-da4aa7f4a63f
DOI: 10.1101/2023.05.12.540486

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Early astrocytic dysfunction is associated to mistuned synapses as well as anxiety and depressive-like behavior in the AppNL-F mouse model of Alzheimers diseaseDOI 10.1101/2023.05.12.540486Read

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